Endocrine Abstracts

Circadian rhythms in behaviours and gene expression are driven by the autonomously rhythmic cells of the hypothalamic suprachiasmatic nucleus (SCN). In nocturnal rodents, restricting a daily meal to the lights-on phase, leads to entrainment of behaviour and gene expression in many extra-SCN hypothalamic nuclei and peripheral tissues. This anticipatory activity is independent of the SCN and is likely to arise from the activities of multiple hypothalamic centres including the do...